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Irwin Fridovich : ウィキペディア英語版 | Irwin Fridovich
Irwin Fridovich is an American biochemist who, together with his graduate student Joe M. McCord, discovered the enzymatic activity of copper,zinc superoxide dismutase (SOD),—to protect organisms from the toxic effects of superoxide free radicals formed as a byproduct of normal oxygen metabolism. Subsequently, Fridovich's research group also discovered the manganese-containing and the iron-containing SODs from E coli and the mitochondrial MnSOD (SOD2), now known to be an essential mammalian protein. He spent the rest of his career studying the biochemical mechanisms of SOD and of biological superoxide toxicity, using bacteria as model systems. Fridovich is currently Professor Emeritus of Biochemistry at Duke University. ==Academic career == From 1951 to 1952, Fridovich served as a medical research associate at Cornell Medical College. He held junior teaching positions in biochemistry at Duke University 1956 to 1961 and was a visiting research associate at Harvard University from 1961 to 1962. He became an assistant professor in biochemistry at Duke University in 1961 and a full professor in 1971. He was appointed as James B. Duke Professor of Biochemistry in 1976 and has held the position as professor emeritus since 1996.
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